Date: Fri, 7 Mar 1997 16:48:30 -0500 
To: richard@ottawa.com X-UIDL: 857772758.005 
From: rwolfson@concentric.net (Richard Wolfson) 
Subject: GE News - Joes Newslette, vol 2 #2 




Gene Tinkering Blues 
Vol. 2 issue 2, January 1996 'Plant-Pesticides' 

Much of the emphasis in crop genetic engineering has been in producing crops containing pesticides or organisms that can be sprayed on crops to destroy major economic pests of the crops. Such genetically engineered forms for fighting crop diseases are called 'Plant-Pesticides'. Crops resistant to insects because they contain Bt Toxin or virus resistance factors (mainly genes from the viruses) are being marketed. An insect virus, Baculovirus, is being modified with genes, such as scorpion toxin gene, diuretic hormone gene, juvenile hormone gene or mite toxin gene to make a potent insect virus to spray on crop plants to protect the crops from insect pests. 

The United States Environmental Protection Agency (EPA) determined that such modified crops and viruses should be regulated like chemical pesticides but the companies patenting the modified crops argued that food should not be labeled as being pesticides. Pesticides require extensive acute and chronic tests to assure that they are safe. Such tests are very expensive and slow the release of gene tinkered products. The giant seed company Northrop King (now named Novartis Seed) was fined for importing Bt tinkered corn seeds from South America that had not been approved by EPA. The fine was very small ($162,500) and the EPA officials were almost apologetic about the law breaking. In Canada, government officials try to avoid upsetting large companies who pay them handsomely (see the last issue of Gene Tinkering Blues 'Paying Off Agriculture Canada'). 

The biotechnology industry has launched a huge propaganda campaign warning of negative consequences if the amount of required safety-testing and regulation on these 'plant pesticides' is raised. The biotech industry says increased regulation would result in: - Increased expense for developing pest resistant forms - The growth of bureaucracy - Use of more chemical pesticides - A competitive disadvantage for US Biotechnology The biotechnology industry wants its products to be tested by consumers and they wish to avoid the liability resulting from pesticide poisoning whether in crops or chemical sprays. 

The use of plant- pesticides is not a new idea: 'natural' tolerance to insects, fungus and bacteria has been selected by plant breeders well before the science of genetics was understood. Unfortunately such pesticides are as likely to cause cancer, birth defects, nerve damage or reduced immunity as their man-made chemical relatives. Celery was treated with gene damaging chemicals and an insect resistant form was selected. The natural production of a natural insecticide, psoralen, was enhanced to make a highly resistant variety. Unfortunately the insect tolerant variety caused skin problems in celery pickers and produce managers in supermarkets, the celery caused cancer in experimental mice. The modified variety had to be withdrawn from the market. The celery incident is typical of plant-pesticides which are frequently chemicals produced by plants in response to stress from the attack of pests. 

Of the natural pesticides tested, a sizable proportion are carcinogens while many others are mutagens. The known carcinogens include estragole (basil), safrole (natural root beer), symphytine (comfrey tea), hydrazine (mushrooms) and allyl isothiocyanate (brown mustard). These plant-pesticides are not threatening until their levels are amplified in the crops using genetic engineering. 

There is clearly evidence that plant-pesticides are likely to be cancer causing and to cause other problems such as skin rashes or nerve damage typical of the man made pesticides. Such pesticides must be tested to protect the public. 

Agriculture Canada has not been very happy about regulating man made pesticides and seems to prefer to ignore plant-pesticides. For example, the herbicide Glyphosate (Round-Up) is used on grains including barley and wheat, oil seeds including Canola and soybean, along with dry pea, lentil and white bean during the fall to hasten the maturation of the crop seeds. A 1994 study showed that about 8% of the crops were treated with Glyphosate (while 20% of the white beans were sprayed with Glyphosate) even though such use was not yet allowed by federal registration. The government responded to such illegal application of a pesticide by changing the regulation retroactively to permit the illegal applications. The government would prefer to ignore the clear and present danger posed by plant-pesticides to allow rapid growth of an unhealthy industry. The illness and suffering caused by the crops will be ignored for the present. 

Average people will have to ensure that the government bureaucrats are controlled by politicians and not visa-versa. Plant-pesticides must be labeled in the market and adequately tested in the laboratory. 

References: 
ISB News Report-January 1997 "EPA Oversight of Plant-Pesticides" 
Gene Exchange 7, Dec.1996 "EPA fines Northrup King over Bt corn" 
Risk Assessment ed.B.Paustenbach, Wiley 1989 B.Ames, R.Magaw and L.Gold 
"Ranking Possible Carcinogens: One Approach to Risk Management " pp1082-1104 

Prof .Joe Cummins, 
Emeritus Professor of Genetics 
University of Western Ontario 
738 Wilkins Street 
London, Ontario N6C4Z9 Canada 
phone&FAX 519 681 5477 
E-Mail: jcummins@julian.uwo.ca 





Richard Wolfson, PhD 
Campaign to Ban Genetically Engineered Food 
Natural Law Party 
500 Wilbrod Street 
Ottawa, ON K1N 6N2 
Tel. 613-565-8517 Fax. 613-565-6546 
E-Mail: rwolfson@concentric.net 

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